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Medical Articles 8

Effect of low frequency electromagnetic fields on A2A adenosine receptors in human neutrophils

Abstract The present study describes the effect of low frequency, low energy, pulsing electromagnetic fields (PEMFs) on A2A adenosine receptors in human neutrophils. Saturation experiments…

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Transcranial magnetic stimulation as a therapeutic tool in psychiatry: what do we know about the neurobiological mechanisms?

Abstract Potential therapeutic properties of repetitive transcranial magnetic stimulation (rTMS) have been suggested in several psychiatric disorders such as depression, mania, obsessive-compulsive disorder, posttraumatic stress…

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Pulsed electromagnetic fields in knee osteoarthritis: a double blind, placebo-controlled, randomized clinical trial

Abstract OBJECTIVES: This trial aimed to test the effectiveness of a wearable pulsed electromagnetic fields (PEMF) device in the management of pain in knee OA…

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Therapeutic application of repetitive transcranial magnetic stimulation: a review

Abstract Transcranial magnetic stimulation (TMS), a non-invasive means of electrically stimulating neurons in the human cerebral cortex, is able to modify neuronal activity locally and…

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Pulsed electromagnetic field therapy for management of osteoarthritis-related pain, stiffness and physical function: clinical experience in the elderly

Abstract BACKGROUND: Pulsed electromagnetic field (PEMF) therapy has shown promising therapeutic effectiveness on bone- and cartilage-related pathologies, being also safe for management of knee osteoarthritis.…

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Repetitive transcranial magnetic stimulation of the human prefrontal cortex induces dopamine release in the caudate nucleus

Abstract Dopamine is implicated in movement, learning, and motivation, and in illnesses such as Parkinson’s disease, schizophrenia, and drug addiction. Little is known about the…

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Striatal dopaminergic metabolism is increased by deep brain stimulation of the subthalamic nucleus in 6-hydroxydopamine lesioned rats

Abstract Deep brain stimulation of the subthalamic nucleus is an established therapeutic strategy for patients with Parkinson’s disease. Although the exact mechanisms of action remain…

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Physical mechanisms in neuroelectromagnetic therapies

Abstract Physical parameters that are used to characterize different types of electromagnetic devices used in neurotherapy can include power, frequency, carrier frequency, current, magnetic field…

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Transcranial magnetic stimulation: Neurophysiological applications and safety

Abstract TMS is a non-invasive tool for measuring neural conduction and processing time, activation thresholds, facilitation and inhibition in brain cortex, and neural connections in…

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Non-invasive electromagnetic field therapy produces rapid and substantial pain reduction in early knee osteoarthritis: a randomized double-blind pilot study

Abstract This study examined whether a non-thermal, non-invasive, pulsed electromagnetic field (PEMF), known to modulate the calmodulin (CaM)-dependent nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signaling…

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Mechanisms and state of the art of transcranial magnetic stimulation

Abstract In 1985, Barker et al. built a transcranial magnetic stimulation (TMS) device with enough power to stimulate dorsal roots in the spine. They quickly…

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Bone density changes in osteoporosis-prone women exposed to pulsed electromagnetic fields (PEMFs)

Abstract To determine the effect of a 72 Hz pulsating electromagnetic field (PEMF) on bone density of the radii of osteoporosis-prone women, the nondominant forearms…

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High frequency repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex in schizophrenic patients

Abstract Repetitive transcranial magnetic stimulation (rTMS) has been tried therapeutically in major depression. In order to investigate the therapeutic efficacy of rTMS in psychotic patients,…

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The effect of long-term pulsing electromagnetic field stimulation on experimental osteoporosis of rats

Abstract The author performed experiments in order to investigate what biological effect on the bone would be produced by long-term pulsing electromagnetic field (PEMF) systemic…

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Influence of electromagnetic fields on the emotional behaviour of rats [Russian]

Abstract The effects of ultra low power pulse-width + modulation electromagnetic radiation (EMR, power density 10 mc/Wt/cm2, carrying frequency 915 MHz, modulating pulses with frequency…

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Acute transcranial magnetic stimulation of frontal brain regions selectively modulates the release of vasopressin, biogenic amines and amino acids in the rat brain

Abstract Using intracerebral microdialysis in urethane-anaesthetized adult male Wistar rats, we monitored the effects of acute repetitive transcranial magnetic stimulation (rTMS; 20 trains of 20…

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Electrochemical therapy of pelvic pain: effects of pulsed electromagnetic fields (PEMF) on tissue trauma

Abstract Unusually effective and long-lasting relief of pelvic pain of gynaecological origin has been obtained consistently by short exposures of affected areas to the application…

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Long-term repetitive transcranial magnetic stimulation increases the expression of brain-derived neurotrophic factor and cholecystokinin mRNA, but not neuropeptide tyrosine mRNA in specific areas of rat brain

Abstract Repetitive transcranial magnetic stimulation (rTMS) is increasingly used as a therapeutic tool in various neurological and psychiatric disorders, and we recently found that it…

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Comparison between the analgesic and therapeutic effects of a musically modulated electromagnetic field (TAMMEF) and those of a 100 Hz electromagnetic field: blind experiment on patients suffering from cervical spondylosis or shoulder periarthritis

Abstract The analgesic-therapeutic efficacy and tolerability of a low-frequency electromagnetic field (ELF), modulated at a frequency of 100 Hz with a sinusoidal waveform and mean…

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Repetitive transcranial magnetic stimulation in rats: evidence for a neuroprotective effect in vitro and in vivo.

Abstract In recent years, repetitive transcranial magnetic stimulation (rTMS) of the human brain has been used as a therapeutic tool in a variety of psychiatric…

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Effects of static magnets on chronic knee pain and physical function: a double-blind study

Abstract CONTEXT: Static magnets have become an increasingly popular alternative therapy for individuals with musculoskeletal pain despite limited scientific evidence to support their efficacy or…

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Chronic repetitive transcranial magnetic stimulation alters beta-adrenergic and 5-HT2 receptor characteristics in rat brain

Abstract Repetitive transcranial magnetic stimulation (rTMS) has been shown to affect mood in health and disease. Evidence to date has demonstrated an antidepressant potential for…

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Pineal-hypothalamic tract mediation of picotesla magnetic fields in the treatment of neurological disorders

Abstract The objective of this study is analysis of the clinical efficacy of picotesla magnetic fields in the treatment of epilepsy, Parkinson’s disease and multiple…

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Safety of the magnetic field generated by a neuronal magnetic stimulator: evaluation of possible mutagenic effects

Abstract OBJECTIVE: The possible mutagenicity of a magnetic stimulus was checked using the Ames test with Salmonella typhimurium TA98 and TA100 as tester strains. METHODS:…

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Pain relief induced by repetitive transcranial magnetic stimulation of precentral cortex

Abstract Chronic electrical stimulation of the precentral (motor) cortex using surgically implanted electrodes is performed to treat medication-resistant neurogenic pain. The goal of this placebo-controlled…

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Differential intensity-dependent effects of magnetic stimulation on the longest neurites and shorter dendrites in neuroscreen-1 cells

Abstract OBJECTIVE: Magnetic stimulation (MS) is a potential treatment for neuropsychiatric disorders. This study investigates whether MS-regulated neuronal activity can translate to specific changes in…

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Therapeutic efficacy of bilateral prefrontal slow repetitive transcranial magnetic stimulation in depressed patients with Parkinson’s disease: an open study

Abstract Recent studies have suggested that both high- and low-frequency repetitive transcranial magnetic stimulation (rTMS) have antidepressant effects in patients with major depression. We conducted…

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Transcranial magnetic stimulation of the cerebellum in essential tremor: a controlled study

Abstract BACKGROUND: Growing evidence implicates an overactivity of the cerebellum in the pathophysiology of essential tremor. In a small series of patients, we explored the…

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Attenuation of interleukin-1beta by pulsed electromagnetic fields after traumatic brain injury

Abstract Traumatic Brain Injury (TBI) is a major cause of morbidity and mortality in civilian and military populations. Interleukin-1beta (IL-1β) is a pro-inflammatory cytokine with…

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The effects of repetitive transcranial magnetic stimulation (rTMS) in the patients with Parkinson’s disease [Japanese]

Abstract The 1-Hz rTMS of 320 stimuli with an intensity of 90% of motor threshold was applied over the vertex of the skull using a…

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A multivariate approach to the treatment of peripheral nerve transection injury: the role of electromagnetic field therapy

Abstract A multivariate approach to the treatment of peripheral nerve transection injury has been used in a rat model. A pilot study (48 animals, 8…

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Contralateral and ipsilateral repetitive transcranial magnetic stimulation in Parkinson patients [German]

Abstract In seven women and two men with Parkinson’s disease, Hoehn and Yahr stage 1 or 2, the effect of repetitive transcranial magnetic stimulation (rTMS)…

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Effectiveness of magnetotherapy in optic nerve atrophy. A preliminary study [Russian]

Abstract Magnetotherapy effects on visual functions (vision acuity and field), on retinal bioelectric activity, on conductive vision system, and on intraocular circulation were studied in…

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Effect of slow repetitive transcranial magnetic stimulation on depression in patients with Parkinson ‘s disease [Cyrillic]

Abstract Parkinson’s disease (PD), that has usually been associated with movement disorders, is also associated with depression in about 40% of patients [9]. Transcranial magnetic…

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Directed and enhanced neurite growth with pulsed magnetic field stimulation

Abstract Pulsed magnetic field (PMF) stimulation was applied to mammalian neurons in vitro to influence axonal growth and to determine whether induced current would direct…

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Therapeutic effect and mechanism of repetitive transcranial magnetic stimulation in Parkinson’s disease

Abstract The therapeutic effect of repetitive transcranial magnetic stimulation (rTMS) on clinical performance was assessed by a double-blind study in 9 patients with Parkinson’s disease…

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Cerebral hemodynamics in patients with neurosensory hearing loss before and after magnetotherapy [Russian]

Abstract Magnetotherapy effects on cerebral hemodynamics were studied using rheoencephalography (REG). When the treatment results and changes in cerebral hemodynamics were compared it was evident…

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Effect of slow repetitive transcranial magnetic stimulation on depression in patients with Parkinson disease [Cyrillic]

Abstract Recent studies have suggested that both high- and low-frequency repetitive transcranial magnetic stimulation (rTMS) have antidepressant effects in patients with major depression. We conducted…

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Enhanced expression of neuronal nitric oxide synthase and phospholipase C-gamma1 in regenerating murine neuronal cells by pulsed electromagnetic field

Abstract Pulsed electromagnetic field (PEMF) has been shown to improve the rate of peripheral nerve regeneration. In the present study we investigated the expression of…

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Nonlinear analysis of brain activity in magnetic influenced Parkinson patients

Abstract Magnetoencephalogram (MEG) recordings were obtained from the brain of patients suffering from Parkinson’s disease (PD) using the Superconductive Quantum Interference Device (SQUID). For each…

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Growth and differentiation of PC6 cells: the effects of pulsed electromagnetic fields (PEMF)

Abstract Previous studies in our laboratory showed that neurite outgrowth in vitro and nerve regeneration in vivo were stimulated by 2 Hz, 0.3 mT (3…

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Akinesia in Parkinson’s disease. II. Effects of subthreshold repetitive transcranial motor cortex stimulation

Abstract We studied the effects of repetitive transcranial stimulation of the motor cortex (rTMS) on choice reaction time (cRT), movement time (MT), and error rate…

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Stimulation of rat sciatic nerve regeneration with pulsed electromagnetic fields

Abstract The effects of pulsed electromagnetic fields (PEMF) on rat sciatic nerve regeneration after a crush lesion were determined. The rats were placed between a…

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Magnetic fields in the treatment of Parkinson’s disease

Abstract Levodopa-induced dyskinesias are a common complication of chronic dopaminergic therapy in patients with Parkinson’s disease (PD). The overall prevalence of levodopa-induced dyskinesias ranges from…

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An experimental study of the effects of pulsed electromagnetic field (Diapulse) on nerve repair

Abstract This study investigates the effects of a pulsed electromagnetic field (PEMF) (Diapulse) on experimentally divided and sutured common peroneal nerves in rats. Evidence is…

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Effect of weak, pulsing electromagnetic fields on neural regeneration in the rat

Abstract The short- and long-term effects of pulsed electromagnetic fields (PEMFs) on the rate and quality of peripheral nerve regeneration were studied. High bilateral transections…

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Effect of bioresonance therapy on antioxidant system in lymphocytes in patients with rheumatoid arthritis

Abstract We measured activities of superoxide dismutase, catalase, and glutathione peroxidase and content of nonprotein thiol groups (reduced glutathione) in blood lymphocytes from patients with…

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Effects of high-peak pulsed electromagnetic field on the degeneration and regeneration of the common peroneal nerve in rats

Abstract Apart from preliminary notices of present work, previous reports of experimental and clinical trials of the effects of a high-peak pulsedelectromagnetic field (PEMF) on…

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Pretreatment of rats with pulsed electromagnetic fields enhances regeneration of the sciatic nerve

Abstract Regeneration of the sciatic nerve was studied in rats pretreated in a pulsed electromagnetic field (PEMF). The rats were exposed between a pair of…

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Effects of a pulsed electromagnetic therapy on multiple sclerosis fatigue and quality of life: a double-blind, placebo controlled trial

Abstract CONTEXT: There is a growing literature on the biological and clinical effects of pulsed electromagnetic fields. Some studies suggest that electromagnetic therapies may be…

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A study of the effects of pulsed electromagnetic field therapy with respect to serological grouping in rheumatoid arthritis

Abstract The positive role of pulsed electromagnetic field (PEMF) therapy in rheumatoid arthritis (RA) is known. The differential role of serological status of patients in…

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Sleep deprivation in depression stabilizing antidepressant effects by repetitive transcranial magnetic stimulation

Abstract Partial sleep deprivation (PSD) has a profound and rapid effect on depressed mood. However, the transient antidepressant effect of PSD – most patients relapse…

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PEMF may improve fatigue associated with multiple sclerosis

Abstract Fatigue is the most common symptom of multiple sclerosis. 75%-90% of patients with multiple sclerosis report having fatigue, and 50%-60% describe it as the…

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Applications of transcranial magnetic stimulation in movement disorders

Abstract The author reviews the applications of transcranial magnetic stimulation (TMS) in a series of movement disorders–namely, Parkinson’s disease, corticobasal degeneration, multiple system atrophy, progressive…

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Exposure to oscillating magnetic fields influences sensitivity to electrical stimuli. II. Experiments on humans

Abstract To assess the effect of a magnetic treatment on pain perception, we compared the sensory threshold in 18 healthy volunteers. We determined the threshold…

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Impulse magnetic-field therapy for migraine and other headaches: a double-blind, placebo-controlled study

Abstract This double-blind, placebo-controlled study assessed the efficacy of 4 weeks of impulse magnetic-field therapy (16 Hz, 5 microTs), delivered through a small device, for…

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